Glycopyrrolate injection

What is glycopyrrolate injection?

GLYCOPYRROLATE (Robinul®) helps relieve spasms in the stomach and bowel. It helps treat peptic ulcer disease or irritable bowel syndrome. It can be used before surgery to reduce body secretions (fluids) and to control your heart rate and blood pressure. Generic glycopyrrolate injections are available.

What should my health care professional know before I receive glycopyrrolate?

They need to know if you have any of these conditions:

• asthma

• difficulty passing urine

• glaucoma

• heart disease or irregular heartbeat

• hiatal hernia

• high blood pressure

• intestinal problems

• kidney disease

• liver disease

• myasthenia gravis

• nervous system disease

• over active thyroid

• stomach obstruction

• ulcerative colitis

• an unusual or allergic reaction to glycopyrrolate, other medicines, foods, dyes, or preservatives

How should I use this medicine?

Glycopyrrolate is for injection into a muscle or into a vein. It is given by a health care professional in a hospital or clinic setting.

What if I miss a dose?

This does not apply.

What drug(s) may interact with glycopyrrolate?

• bethanechol

• cisapride

• disopyramide

• donepezil

• erythromycin

• galantamine

• medicines for hay fever and other allergies

• medicines for mental depression

• medicines for mental problems and psychotic disturbances

• metoclopramide

• rivastigmine

• tacrine

• tegaserod

Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking glycopyrrolate?

You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how glycopyrrolate affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more drowsy, avoid alcoholic drinks.

Avoid extreme heat (e.g., hot tubs, saunas). Glycopyrrolate can cause you to sweat less than normal. Your body temperature could increase to dangerous levels, which may lead to heat stroke.

If you get constipation while receiving glycopyrrolate, do not treat yourself. You may have a blockage in the intestine. Call your prescriber or health care professional for advice.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help.

What side effects may I notice from receiving glycopyrrolate?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• agitation, nervousness, confusion

• blurred vision and other eye problems

• decreased sweating

• dizziness, drowsiness

• irregular heartbeat (palpitations)

• pain or difficulty passing urine

• unusual weakness or tiredness

• vomiting

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• constipation

• difficulty sleeping

• dry mouth, change in taste

• headache

• nausea

• sexual difficulty (impotence)

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Glycopyrrolate tablets

What are glycopyrrolate tablets?

GLYCOPYRROLATE (Robinul®) helps relieve spasms in the stomach and bowel. It helps treat peptic ulcer disease or irritable bowel syndrome. Generic glycopyrrolate tablets are not yet available.

What should my health care professional know before I take glycopyrrolate?

They need to know if you have any of these conditions:

• difficulty passing urine

• glaucoma

• heart disease or irregular heartbeat

• hiatal hernia

• high blood pressure

• intestinal problems

• kidney disease

• myasthenia gravis

• nervous system disease

• over active thyroid

• stomach obstruction

• ulcerative colitis

• an unusual or allergic reaction to glycopyrrolate, other medicines, foods, dyes, or preservatives

How should I take this medicine?

Take glycopyrrolate tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with glycopyrrolate?

• bethanechol

• cisapride

• disopyramide

• donepezil

• erythromycin

• galantamine

• medicines for hay fever and other allergies

• medicines for mental depression

• medicines for mental problems and psychotic disturbances

• metoclopramide

• rivastigmine

• tacrine

• tegaserod

Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking glycopyrrolate?

You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how glycopyrrolate affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more drowsy, avoid alcoholic drinks.

Avoid extreme heat (e.g., hot tubs, saunas). Glycopyrrolate can cause you to sweat less than normal. Your body temperature could increase to dangerous levels, which may lead to heat stroke.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help.

If you get constipation while receiving glycopyrrolate, do not treat yourself. You may have a blockage in the intestine. Call your prescriber or health care professional for advice.

What side effects may I notice from taking glycopyrrolate?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• agitation, nervousness, confusion

• blurred vision and other eye problems

• decreased sweating

• dizziness, drowsiness

• irregular heartbeat (palpitations)

• pain or difficulty passing urine

• unusual weakness or tiredness

• vomiting

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• constipation

• difficulty sleeping

• dry mouth, change in taste

• headache

• nausea

• sexual difficulty (impotence)

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.