Picture of branding placeholder

Search Health Information

Go Advanced Search
Related Items; Photo of puzzle pieces

Trospium extended-release capsules

What are Trospium extended-release capsules?

TROSPIUM (Sanctura™ XR) capsules help to control an overactive bladder, a chronic condition that can be improved with medication. Trospium may reduce the frequency of bathroom visits and may help to control wetting accidents.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • difficulty passing urine

  • glaucoma

  • intestinal obstruction

  • kidney disease

  • liver disease

  • stomach problems like pyloric stenosis or reflux, or other problems with proper emptying of the contents of the stomach

  • an unusual or allergic reaction to trospium, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should this medicine be used?

Take this medicine by mouth. Swallow the capsules with a drink of water. Take on an empty stomach, at least one hour before eating. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If it is almost time for your next dose, take only that dose on the regular schedule. Do not take double or extra doses.

What drug(s) may interact with Trospium?

  • adefovir

  • alcohol-containing beverages

  • amantadine

  • amiloride

  • atropine

  • caffeine

  • cimetidine

  • cisapride

  • cyclobenzaprine

  • donepezil

  • entecavir

  • galantamine

  • hyoscyamine

  • itraconazole

  • ketoconazole

  • lamivudine, 3TC

  • megestrol

  • memantine

  • metformin

  • metoclopramide

  • midodrine

  • morphine

  • orphenadrine

  • oxybutynin

  • quinine

  • ranitidine

  • rivastigmine

  • scopolamine

  • some antibiotics such as erythromycin, trimethoprim, and vancomycin

  • some medicines for colds, hay fever, or allergies

  • some medicines to control the heart rhythm such as digoxin, disopyramide, dofetilide, procainamide, and quinidine

  • some medicines for mental depression or psychotic disorders

  • tacrine

  • tegaserod

  • tolterodine

  • topiramate

  • triamterene

  • water pills (diuretics)

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking Trospium?

Your health care professional may also recommend techniques that may help improve control of your bladder and sphincter muscles. Such techniques will help train you to need the bathroom less frequently.

You may need to limit your intake of tea, coffee, caffeinated sodas, and alcohol. These drinks may aggravate your symptoms. Keeping healthy bowel habits may lessen bladder symptoms. If you currently smoke, quitting smoking may help reduce irritation to the bladder muscle.

You may get dizzy or have blurred vision. Do not drive, use machinery, or do anything that requires mental alertness until you know how trospium affects you.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water, will help.

This medicine rarely causes dry eyes and blurred vision. If you wear contact lenses, you may feel some discomfort. Lubricating drops may help. See your ophthalmologist if the problem does not go away or is severe.

What side effects may I notice from receiving Trospium?

Serious side effects are not common. Side effects that you should report to your prescriber or health care professional as soon as possible:

  • signs of an allergic reaction, like itching or hives

  • blurred vision or difficulty focusing vision

  • confusion

  • difficulty passing urine

  • severe dizziness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • constipation

  • dry eyes

  • dry mouth

  • headache

  • indigestion or stomach upset

  • mild dizziness or drowsiness

  • nausea

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

Trospium tablets

What are Trospium tablets?

TROSPIUM (Sanctura™) tablets help to control an overactive bladder, a chronic condition that can be improved with medication. Trospium may reduce the frequency of bathroom visits and may help to control wetting accidents. Generic trospium tablets are not yet available.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • difficulty passing urine

  • glaucoma

  • intestinal obstruction

  • kidney disease

  • liver disease

  • stomach problems like pyloric stenosis or reflux, or other problems with proper emptying of the contents of the stomach

  • an unusual or allergic reaction to trospium, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should this medicine be used?

Take trospium tablets by mouth. Swallow the tablets with a drink of water. Trospium should be taken on an empty stomach, at least one hour before eating. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If it is almost time for your next dose, take only that dose on the regular schedule. Do not take double or extra doses.

What drug(s) may interact with Trospium?

  • adefovir

  • alcohol-containing beverages

  • amantadine

  • amiloride

  • atropine

  • caffeine

  • cimetidine

  • cisapride

  • cyclobenzaprine

  • donepezil

  • entecavir

  • galantamine

  • hyoscyamine

  • itraconazole

  • ketoconazole

  • lamivudine, 3TC

  • megestrol

  • memantine

  • metformin

  • metoclopramide

  • midodrine

  • morphine

  • orphenadrine

  • oxybutynin

  • quinine

  • ranitidine

  • rivastigmine

  • scopolamine

  • some antibiotics such as erythromycin, trimethoprim, and vancomycin

  • some medicines for colds, hay fever, or allergies

  • some medicines to control the heart rhythm such as digoxin, disopyramide, dofetilide, procainamide, and quinidine

  • some medicines for mental depression or psychotic disorders

  • tacrine

  • tegaserod

  • tolterodine

  • topiramate

  • triamterene

  • water pills (diuretics)

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking Trospium?

Your health care professional may also recommend techniques that may help improve control of your bladder and sphincter muscles. Such techniques will help train you to need the bathroom less frequently.

You may need to limit your intake of tea, coffee, caffeinated sodas, and alcohol. These drinks may aggravate your symptoms. Keeping healthy bowel habits may lessen bladder symptoms. If you currently smoke, quitting smoking may help reduce irritation to the bladder muscle.

You may get dizzy or have blurred vision. Do not drive, use machinery, or do anything that requires mental alertness until you know how trospium affects you.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water, will help.

Trospium rarely causes dry eyes and blurred vision. If you wear contact lenses, you may feel some discomfort. Lubricating drops may help. See your ophthalmologist if the problem does not go away or is severe.

What side effects may I notice from receiving Trospium?

Serious side effects are not common. Side effects that you should report to your prescriber or health care professional as soon as possible:

  • any signs of an allergic reaction, like itching or hives

  • blurred vision or difficulty focusing vision

  • confusion

  • difficulty passing urine

  • severe dizziness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • constipation

  • dry eyes

  • dry mouth

  • headache

  • indigestion or stomach upset

  • mild dizziness or drowsiness

  • nausea

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Publication Source: U.S. FDA-approved Package Insert
Date Last Modified: 8/29/2007